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  • Long read

Rehab centres and the ‘cure’ for addiction

Guy Stagg takes us on a brief history of rehab centres and their approaches to addiction and recovery.

  • Article

Tripping for spiritualism and science

Getting high in the name of religion or creativity has been practised for centuries. Now it seems hallucinogenics could help treat mental illnesses too.

  • Article

Inhaling happiness and gasping for a high

The rapid, short-lived high we get from whippets, reefers and vapes can be accompanied by long-term health consequences. The search is on for safer ways to get stoned.

  • Article

A history of mindfulness

Matt Drage questions how an ancient religious practice became a secular cure for stress.

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  • AIDS : issues and perspectives : a conference for everyone wishing to contribute to the public understanding of science : on Saturday 5 December 1992, 10.00am - 4.30 pm at Channel 4 Preview Studio, 44 Whitfield Street, London W1 / Birkbeck College University of London Centre for Extra-Mural Studies in association with Channel Four Television.
  • AIDS : issues and perspectives : a conference for everyone wishing to contribute to the public understanding of science : on Saturday 5 December 1992, 10.00am - 4.30 pm at Channel 4 Preview Studio, 44 Whitfield Street, London W1 / Birkbeck College University of London Centre for Extra-Mural Studies in association with Channel Four Television.
  • AIDS : issues and perspectives : a conference for everyone wishing to contribute to the public understanding of science : on Saturday 5 December 1992, 10.00am - 4.30 pm at Channel 4 Preview Studio, 44 Whitfield Street, London W1 / Birkbeck College University of London Centre for Extra-Mural Studies in association with Channel Four Television.
  • AIDS : issues and perspectives : a conference for everyone wishing to contribute to the public understanding of science : on Saturday 5 December 1992, 10.00am - 4.30 pm at Channel 4 Preview Studio, 44 Whitfield Street, London W1 / Birkbeck College University of London Centre for Extra-Mural Studies in association with Channel Four Television.
  • Rudbeckia triloba L. Asteraceae Orange Cone flower. Herbaceous perennial. Distribution: North America. It is named for Olof Rudbeck, father (1630–1702) and son (1660–1740). Olof Rudbeck the Elder was professor of medicine at Uppsala University, and established a botanic garden there. He was the discoverer of the human lymphatic system. His son succeeded his father as professor of medicine, and one of his students was Carl Linnaeus (1707–88) who named the genus Rudbeckia after him and his father. It is a plant which is poisonous to cattle, sheep and pigs with no medicinal uses. Austin (1974) discusses R. hirta, also regarded as a toxic plant. It was used externally by the Cherokee to bathe sores and snakebites and made into a tea for treating diarrhoea. The Seminoles used it for headaches and fever and the Miccosukee for sunstroke and headache. The Cherokee and the Iroquois used it to treat intestinal worms Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Hacquetia epipactis DC Apiaceae. Small herbaceous perennial. No common name except Hacquetia Distribution: Europe. Named for the Austrian physician, Balthasar (or Belsazar) Hacquet (1739/40-1815). He studied medicine in Vienna, was a surgeon in the brutal Seven Years War (1756-1763) – a world-wide war in which up to 1,400,000 people died. Later he was professor at the University of Lemberg (1788-1810). He wrote widely on many scientific disciplines including geology. Parkinson (1640) grouped it with Helleborus and Veratrum, calling it 'Epipactis Matthioli, Matthiolus, his bastard black hellebore' but does not give any uses. It has no medicinal properties. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Valeriana officinalis L. Valerianaceae Valerianus, Phu, Nardus sylvestris, Setwal. Distribution: Europe. Popular herbalism attributes sedation to Valerian, but this is not mentioned by Coles (1657) or Gerard (1633) or Lobel (1576) or Lyte (1578) or Dioscorides (ex Gunther, 1959) or Fuchs (1553), where he quotes Pliny, Dioscorides and Galen, or Parkinson (1640), or Pomet (1712). The English translation of Tournefort (1719-1730) covers a whole page of the uses of all the different valerians, but never mentions sedation or treating anxiety. Quincy (1718) does not mention it. Because it was used in epilepsy, for which Woodville (1792) says it was useless, Haller, in his Historia stirpium indegenarum Helvetae inchoatae (1768) advocates it for those with irritability of the nervous system, as does Thomson's London Dispensatory (1811) although he lists it as an 'antispasmodic and stimulant' and for inducing menstruation. Lindley (1838) notes (as many did) that the roots smell terrible and that this makes cats excited, and in man, in large doses, induce 'scintillations, agitation and even convulsions' so used in asthenic fever, epilepsy, chorea, hysteria and as an antihelminthic.' Fluckiger & Hanbury (1879) give a wonderful account of the history of its names, but give its use as 'stimulant and antispasmodic' as do Barton & Castle (1877). but by 1936 (Martindale's Extra Pharmacopoeia) its only use was 'Given in hysterical and neurotic conditions as a sedative. Its action has been attributed to its unpleasant smell'. The European Medicines Agency (2006) approves its use as a traditional herbal medicine for mild anxiety and sleeplessness for up to 4 weeks. Despite what is written continuously about its use in ancient Greece and Rome, the only reason for its use has been because it was thought, for a brief while, to be good for epilepsy and therefore might deal with persons of a nervous disposition because of its foul smell. It has been suggested that even its Greek name, 'Phu' came from the expression of disgust which is made when one sniffs an unpleasant odour. For 1,800 years, before the last century, no-one had thought it sedative. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Capsicum annuum 'Masquerade' Distribution: Central and South America. This ‘domesticated species’ originated from Mexico (although the centre of Capsicum evolution was much earlier and from Bolivia) and includes the bland salad peppers and the hot chilli peppers, of which capsaicin (sometimes called capsicain), from the lining of the inside of the chilli, is the main active ingredient. Chilli comes from the Aztec language of the Nahuatl people. It was reputedly introduced to Europe by Columbus in the mid-15th century, but was cultivated in Mexico since 4,000 BCE and used in cooking since 7,200 BCE. After its introduction to Europe, its cultivation very rapidly became world-wide. It appears first as a description (Bock, 1539) with the name teutschem Pfeffer. The first illustration, as Siliquastrum, appears in Historia Stirpes commentarii insignis (Fuchs, 1542). Fuchs did not realise it came from the Americas, as he identified it as a plant described by Pliny, Dioscorides and Avicenna and gave their uses of it. It appear in Dodoen's Cruydeboeck (1551) and Lyte's translation (1557) with the note that it is 'hot and drie in the third degree.' He recommended it for dressing meat, and noted that it 'warmeth the stomach' and was good for a sore throat, scrofula, and topically got rid of spots. Fuch's had reported these properties as being described by Avicenna, but what that plant was is unknown. Lindley (1838) wrote: 'It is employed in medicine, in combination with Cinchona in intermittent and lethargic affections, and also in atonic gout, dyspepsia accompanied by flatulence, tympanitis, paralysis etc. Its most valuable application appears however to be in cynanche maligna [=severe sore throat, with impending suffocation] and scarlatina maligna [=severe scarlet fever], used either as a gargle or administered internally.' However, its principal use medically has been in pain relief, applied locally for pain from muscle injury to post herpetic neuralgia. Capsaicin acts on the pain and heat sensing neurones to make them trigger the sensation of pain at body temperature. Repeated exposure to capsaicin depletes the neurotransmitter substance P that is used to perceive pain, so the relevant nerves no longer transmit the sensation of pain/heat from any cause. It is a banned substance in the equestrian events at the Olympics because of its ability to stop perception of pain. Capsaicin has been shown, experimentally, to kill cancer cells by attacking their mitochondria. Particular interest has concentrated on its ability to reduce the size of tumours of the pancreas and prostate. Various cultivars are used in cooking, and the strength (i.e. how hot they are) is measured in Scoville units. A standard chilli pepper used in England would be around 5,000 Scovilles, the hottest peppers are rated over one million Scoville units. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Bergenia ciliata (Haw.)Sternb. Saxifraginaceae. Elephant's ears. Named for Karl August von Bergen (1704-1759), physician and botanist, professor at Viadrina University, Frankfurt. Has hairy leaves, hence ciliata. Distribution: E. Afghanistan, Himalayas, Assam. Used for fevers, diarrhoea, bruises and boils, coughs, renal stones, diabetes, heart disease, haemorrhoids, stomach disorders (Harish et al www.ijabpt.com). It was described in the 1820s so there is no early literature. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Osmanthus delavayi Franch. Oleaceae Evergreen shrub. Distribution: China. Osmanthus is derived from the Greek for 'fragrant flower', delavayi from its discoverer, the French Missionary with the Missions Étrangères, and plant collector, Pierre Delavay (1834-1895). He sent 200,000 herbarium specimens containing 4000 species including 1,500 new species to Franchet at the Museum of Natural History in Paris. He sent seed of O. delavayi to France (1886), but only one germinated, and all the plants in cultivation until it was recollected 40 years later, arose from this plant (Bretschneider, 1896). The flowers are used to make a tea in China, but the berries (drupes) are not regarded as edible. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
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